It runs 2 of every secret and basically completely disabled the opponent and feeds rodney the right minions.
I beat it a few times but it is a slug. The best thing to do is to hold down your cards and use fodder to pull out his secrets and try to force duplicates early on.
I found most success killing the mas scientists as opposed to letting them run or silence them.
Combos like duplicating a lot of tor mages or w/e theyre called means he can have a lot of strong 4/3's on board and play secrets for free.